IRAK1-IN-1 (compound B8) is an orally active IRAK1 inhibitor. IRAK1-IN-1 inhibits the release of IL-6 with the IC50 values of 4.57 µM and 6.51 µM on mouse cells J774A. 1 and human cells THP-1, respectively. IRAK1-IN-1 alleviats LPS (HY-D1056)-induced acu
Molecular Weight:
316.35
Formula:
C17H20N2O4
Target:
IRAK
Application Notes:
Reference compound
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