LMP517 (NSC 781517) a indenoisoquinoline, is a potent a dual TOP1 and TOP2 inhibitor. LMP517 shows better antitumor activity than its parent compound LMP744 (HY-U00248) against H82 (Small Cell Lung Cancer) xenografts. LMP517 induces TOP1 cleavage complex
Molecular Weight:
410.40
Purity:
99.58
CAS Number:
[1883730-99-1]
Formula:
C22H19FN2O5
Target:
Topoisomerase
Application Notes:
Reference compound
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