BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC50 of 8 nM. BAY-155 leads to a strong expression down-regulation of the MEIS1 gene and up-regulation of CD11b and MNDA genes. BAY-155 shows anti-proliferative effects in AML/ALL (acute
Molecular Weight:
567.63
CAS Number:
[2163769-52-4]
Formula:
C28H28F3N7OS
Target:
Epigenetic Reader Domain
Application Notes:
Reference compound
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