MTX115325 (Example 1) is an orally active, brain-penetrating USP30 inhibitor (IC50=12 nM) with neuroprotective activity. MTX115325 increases ubiquitination (EC50=32 nM) of the mitochondrial outer membrane protein TOM20 (a USP30 substrate), increasing mit
Molecular Weight:
348.36
Purity:
99.08
CAS Number:
[2750895-97-5]
Formula:
C18H16N6O2
Target:
Deubiquitinase,Mitophagy
Application Notes:
Reference compound
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