D3S-001 is an orally active inhibitor for KRAS. D3S-001 inhibits the proliferation of KRASG12C mutant H358 and MIA-PA-CA-2 with an IC50 of 0.6 and 0.44 nM. D3S-001 exhibits good metabolic stability in hepatocytes, liver microsomes, plasma and whole blood
Molecular Weight:
679.66
CAS Number:
[2914919-85-8]
Formula:
C32H35F6N7O3
Target:
Ras
Application Notes:
Reference compound
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