PRO-6E is an oral active PROTAC based on Cereblon ligand, and induces the degradation of MET with maximum degradation of 81.9% at 1 µM in MKN-45 cells. PRO-6E inhibits tumor growth in vivo and in vitro. PRO-6E induces cell apoptosis and induces cell arre
Molecular Weight:
848.75
Purity:
99.85
CAS Number:
[2353493-69-1]
Formula:
C42H44Cl2FN7O7
Target:
Apoptosis,c-Met/HGFR,PROTACs
Application Notes:
Reference compound
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