IBG3 is a dual-JQ1-containing BET degrader that targets protein degradation via intramolecular bivalent glues. IBG3 is a BRD2 and BRD4 bifunctional degrader with DC50 values of 8.6 pM and 6.7 pM, respectively[1].
Molecular Weight:
976.22
Formula:
C54H57N9O5S2
Target:
Epigenetic Reader Domain,Molecular Glues
Application Notes:
Reference compound
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