PF-05214030 is a TRPV4 antagonist (IC50: 4 and 27nM for hTRPV4 and rTRPV4 respectively). PF-05214030 reverses the reduction in bladder capacity caused by intravesical infusion of a TRPV4 agonist[1][2].
Molecular Weight:
431.27
Purity:
99.19
CAS Number:
[1669444-50-1]
Formula:
C17H13Cl2FN2O4S
Target:
TRP Channel
Application Notes:
Reference compound
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