NLRP3-IN-39 (Compound 49) inhibits the assembly and activation of NLRP3 inflammatory vesicles. NLRP3-IN-39 exerts its inhibitory effect by covalently binding to Cys 279 of the NLRP3 protein. NLRP3-IN-39 inhibits Nigericin (HY-127019)-induced IL-1beta releas
Molecular Weight:
422.30
Formula:
C21H21Cl2NO4
Target:
Interleukin Related,NOD-like Receptor (NLR)
Application Notes:
Reference compound
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