DW18134 is an inhibitor for interleukin receptor-associated kinase 4 (IRAK 4) with an IC50 of 11.2 nM. DW18134 inhibits phosphorylation of IRAK4 and IKK, downregulates the secretion of TNF-alpha and IL-6. DW18134 attenuates the Lipopolysaccharides (HY-D1056)
Molecular Weight:
427.46
CAS Number:
[2626988-87-0]
Formula:
C24H21N5O3
Target:
IRAK
Application Notes:
Reference compound
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