SH-E4A-66 is a C2-COUPLr (COvalent Protein Ligator) with carbazole scaffold barring heterogeneous cysteine reactive warheads (acrylamide and chloroacetamide). SH-E4A-66 is capable of coupling with EML4-ALK (EC50=1.5 µM) and inhibiting the activity of EML
Molecular Weight:
431.87
Formula:
C24H18ClN3O3
Target:
Anaplastic lymphoma kinase (ALK)
Application Notes:
Reference compound
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