EGFR-IN-120 (Compound 11eg) is an orally active EGFR inhibitor. EGFR-IN-120 inhibits EGFRL858R/T790M/C797S with an IC50 value of 0.053 µM, and has a relatively weak effect on EGFRWT (IC50: 1.05 µM). EGFR-IN-120 inhibits the phosphorylation of EGFR and ma
Molecular Weight:
570.66
Formula:
C31H35FN8O2
Target:
Akt,Apoptosis,EGFR,ERK
Application Notes:
Reference compound
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