YGT-31 is a modulator for PPARgamma with an IC50 of 1.72 µM, and a Ki of 0.62 µM. YGT-31 reduces blood glucose levels and improves insulin resistance in db/db mice type 2 diabetes models, through inhibition of CDK5-mediated PPARgamma-Ser273 phosphorylation. YGT-
Molecular Weight:
469.41
CAS Number:
[2835447-74-8]
Formula:
C25H18F3NO5
Target:
PPAR
Application Notes:
Reference compound
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