Z21115 is an orally active inhibitor for phosphodiesterase 4 (PDE4), that inhibits PDE4D7 with IC50 of 10.5 nM. Z21115 inhibits Lipopolysaccharide (HY-D1056)-induced expression of IL-6, TNF-alpha and iNOS. Z21115 exhibits anti-inflammatory activity in DSS (H
Molecular Weight:
390.38
CAS Number:
[2958668-54-5]
Formula:
C20H20F2N2O4
Target:
Phosphodiesterase (PDE)
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted