MeIm (compound 7) is a high-affinity PCSK9 targeting peptide mimetic with cholesterol-lowering activity. MeIm increases cellular uptake of LDL (EC50=6.04 µM) by inhibiting the binding of PCSK9 to LDLR (IC50=11.2 µM). MeIm can be used in the study of card
Molecular Weight:
398.46
CAS Number:
[2043947-71-1]
Formula:
C22H22N8
Target:
LDLR,PCSK9
Application Notes:
Reference compound
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