Top1/2-IN-1 (compound 23) is an orally available dual inhibitor of Top1/2 with antiproliferative activity. Top1/2-IN-1 damages DNA with increased levels of reactive oxygen species, inducing apoptosis and cell cycle arrest in cancer cells. Top1/2-IN-1 exh
Molecular Weight:
347.41
Formula:
C21H21N3O2
Target:
Topoisomerase
Application Notes:
Reference compound
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