DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM. DNA-PK-IN-12 inhibits cell growth and Hct116 cell colony formation with the IC50 of 33.28 µM, and shows antitumor activity in vivo[1].
Molecular Weight:
420.47
Purity:
99.63
CAS Number:
[2792146-91-7]
Formula:
C21H24N8O2
Target:
DNA-PK
Application Notes:
Reference compound
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