AB-452, a Dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer. AB-452 inhibits PAPD5/7 proteins in vitro with good in vivo efficacy in a chronic HBV mouse model[1].
Molecular Weight:
402.44
CAS Number:
[2226178-35-2]
Formula:
C21H26N2O6
Target:
HBV
Application Notes:
Reference compound
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