Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38alpha and p38beta, respectively, and can be used in the research of acute myeloid leukemia.
Molecular Weight:
556.63
Purity:
99.89
CAS Number:
[945614-12-0]
Formula:
C31H33FN6O3
Target:
Autophagy,p38 MAPK,Tie
Application Notes:
Reference compound
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