Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe r
Molecular Weight:
365.39
Purity:
98.74
CAS Number:
[1234015-52-1]
Formula:
C18H19N7O2
Target:
Apoptosis,Checkpoint Kinase (Chk)
Application Notes:
Reference compound
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