Zorifertinib (AZD3759) is a potent, orally active, central nervous system-penetrant, EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.3, 0.2, and 0.2 nM for EGFRwt, EGFRL858R, and EGFRexon 19Del, respectively. Zorifertinib induces cancer cell ap
Molecular Weight:
459.90
Purity:
99.76
CAS Number:
[1626387-80-1]
Formula:
C22H23ClFN5O3
Target:
Apoptosis,EGFR
Application Notes:
Reference compound
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