IN-1130 is a highly selective transforming growth factor-beta type I receptor kinase (ALK5) inhibitor with an IC50 of 5.3 nM for ALK5-mediated Smad3 phosphorylation. IN-1130 inhibits ALK5 phosphorylation of casein (IC50=36 nM) and p38alpha mitogen-activated pro
Molecular Weight:
420.47
Purity:
99.79
CAS Number:
[868612-83-3]
Formula:
C25H20N6O
Target:
TGF-beta Receptor
Application Notes:
Reference compound
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