EW-7195 is a potent and selective ALK5 (TGFbetaR1) inhibitor with an IC50 of 4.83 nM. EW-7195 has >300-fold selectivity for ALK5 over p38alpha. EW-7195 efficiently inhibits TGF-beta1-induced Smad signaling, epithelial-to-mesenchymal transition (EMT) and breast tum
Molecular Weight:
406.44
Purity:
99.20
CAS Number:
[1352609-28-9]
Formula:
C23H18N8
Target:
p38 MAPK,TGF-beta Receptor
Application Notes:
Reference compound
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