JI6 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ~40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits JAK3 and c-Kit, with IC50s of ~250 and ~500 nM, respectively. JI6 can be used for the res
Molecular Weight:
383.42
CAS Number:
[856436-16-3]
Formula:
C19H17N3O4S
Target:
c-Kit,FLT3,JAK
Application Notes:
Reference compound
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