SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity[1][2].
Molecular Weight:
562.50
Purity:
99.19
CAS Number:
[1303607-60-4]
Formula:
C29H34Cl2FN3O3
Target:
Apoptosis,E1/E2/E3 Enzyme,MDM-2/p53
Application Notes:
Reference compound
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