LXW7, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin alphavbeta3 inhibitor. LXW7 has a high binding affinity to alphavbeta3 integrin with an IC50 of 0.68 µM. LXW7 increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory effect[1]
Molecular Weight:
820.89
CAS Number:
[1313004-77-1]
Formula:
C29H48N12O12S2
Target:
Integrin
Application Notes:
Peptides
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