aStAx-35R TFA, a stapled peptide, antagonizes nuclear form of beta-catenin and inhibits Wnt signaling. aStAx-35R TFA inhibits competitively the binding of beta-catenin to TCF4. aStAx-35R TFA selectively induces growth inhibition of Wnt-dependent cancer cells[1
Molecular Weight:
2392.86 (free base)
Purity:
98.43
Formula:
C111H178N40O20.xC2HF3O2
Target:
Wnt,beta-catenin
Application Notes:
Peptides
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