Klotho-derived peptide 1 (KP1 human) blocks TGF-beta/TGF-beta receptor 2 interaction, inhibits TGF-beta-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model[1].
Molecular Weight:
3228.44
Formula:
C149H203N39O43
Target:
p38 MAPK,TGF-beta/Smad
Application Notes:
Peptides
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