COG 133 is a fragment of Apolipoprotein E (APOE) peptide. COG 133 competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 is also a nAChR antagonist with an IC50 of 445 nM[1][2].
Molecular Weight:
2169.71
CAS Number:
[514200-66-9]
Formula:
C97H181N37O19
Target:
Apolipoprotein,nAChR
Application Notes:
Peptides
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