TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is a potent CXCR7 agonist with an EC50 of 350 nM for recruiting beta-arrestin 2 to CXCR7. TC14012 has anti-HIV activity and anti-
Molecular Weight:
2066.42
Purity:
99.9
CAS Number:
[368874-34-4]
Formula:
C90H140N34O19S2
Target:
CXCR,HIV
Application Notes:
Peptides
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