IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, in
Molecular Weight:
Approximately 27 kDa
Purity:
98
Formula:
3480(Gene_ID)P08069 (Y763-E931)(Accession)
Application Notes:
Recombinant Proteins
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