DKK-3 protein antagonizes canonical Wnt signaling by blocking LRP5/6-Wnt interactions and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization. In vertebrate development, DKK-3, together with other DKKs, critically inhibits Wnt
Molecular Weight:
Approximately 66-73 kDa
Purity:
95
Formula:
27122(Gene_ID)Q9UBP4 (A22-I350)(Accession)
Application Notes:
Recombinant Proteins
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