DPBQ activates p53 and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerase or bind DNA. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells[1].
Molecular Weight:
362.38
Purity:
99.02
CAS Number:
[7029-89-2]
Formula:
C24H14N2O2
Target:
Apoptosis,MDM-2/p53
Application Notes:
Reference compound
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