PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities[1].
Molecular Weight:
236.63
Purity:
99.56
CAS Number:
[38275-34-2]
Formula:
C6H5ClN2O4S
Target:
DNA Alkylator/Crosslinker,MDM-2/p53
Application Notes:
Reference compound
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