Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 µM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes[1][
Molecular Weight:
366.11
Purity:
98.57
CAS Number:
[1477-57-2]
Formula:
C12H20Cl4N2O2
Target:
Aldehyde Dehydrogenase (ALDH)
Application Notes:
Reference compound
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