2-O-Methylguanosine-d3 is deuterium labeled 2-O-Methylguanosine (HY-W013260). 2-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2-O-methyltransferase. 2-O-Methylguanosine results in apoptotic changes of cells