AP-18, a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 µM Cinnamaldehyde with an IC50 of 3.1 µM and 4.5 µM for human and mouse TRPA1, respectively. AP-18 reverses complete Freunds adjuvant (CFA)-induced mechanical hyperalgesia in
Molecular Weight:
209.67
Purity:
99.80
CAS Number:
[55224-94-7]
Formula:
C11H12ClNO
Target:
TRP Channel
Application Notes:
Reference compound
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