PDGFRalpha kinase inhibitor 2 (compound 1), an Imatinib (HY-15463) analogue, is a covalent and irreversible kinase inhibitor with IC50s of 6.95 µM, 2.45 µM, 1.39 µM for ABL1 wt, KIT wt, PDGFRR wt[1].
Molecular Weight:
429.90
Purity:
98
CAS Number:
[404844-11-7]
Formula:
C24H20ClN5O
Target:
Bcr-Abl,c-Kit,PDGFR
Application Notes:
Reference compound
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