SMART1 is a highly specific and CRBN-dependent PROTAC that can effectively degrade Smurf1. SMART1 can block the PDK1-Akt signaling pathway in KRAS mutant colorectal cancer. SMART1 can inhibit tumor growth in KRAS mutant colorectal cancer (CRC) xenograft
Molecular Weight:
753.76
Formula:
C40H35N9O7
Target:
Akt,PDK-1,PROTACs
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
