ANTcryo ANTA Cryo-EM Grids (Au300-R1.2/1.3)

Product Overview

• Article Name: ANTcryo ANTA Cryo-EM Grids (Au300-R1.2/1.3)
• Biozol Catalog Number: MDL-MDL-M01
• Supplier Catalog Number: MDL-M01
• Alternative Catalog Number: MDL-MDL-M01
• Manufacturer: Molecular Dimension
• Category: Sonstiges

Product Description

ANTcryo ANTA Cryo-EM Grids (Au300-R1.2/1.3) - 50 Grids

Additional Information

Amorphous Ni-Titanium Holey Grids (pack of 50):

Grid Type: Gold (Au)

Mesh Size: 300

Aperture Pitch: 1.2/1.3

 

ANTcryo holey support film (Amorphous Nickel Titanium alloy Grid) is a new and sophisticated solution for cryo-EM singleparticle sample preparation.

1 - Improving the resolution of reconstruction
ANTcryo™ Grids offer increased resolution compared to carbon grids due to their superior conductivity, resulting in reduced electron charging effects and less beam-induced motion (BIM) during cryo-EM imaging. This improvement enables the achievement of higher-resolution structures, with user experiments demonstrating an improvement of more than 0.2 Å in resolution.

2 - Improving the rate of sample preparation
ANTcryo™ support film exhibits an adsorption force nearly 20 times lower than traditional carbon film, thereby enhancing the particle inlet rate and reducing particle aggregation within the pore. This improvement significantly enhances the success rate of sample preparation by improving particle dispersion.

3 - Improving the efficiency of data collection
With the contribution of higher particle density, users need much less EM time for data collection for the same number of particles.
Similar to carbon films, ANTcryoTM Grids are made of amorphous material that is suitable for coma alignment. Unlike gold films, ANTA film’s amorphous structure allows routine TEM alignment like carbon films (defocus estimation, stigmatism adjustment, comafree alignment). This eliminates challenges associated with gold’s polycrystalline nature, simplifying cryo-EM workflows and saving valuable research time.

 

 

Images

ANTcryo ANTA Cryo-EM Grids

Cryo-EM photo of apoferritin Compared with traditional carbon membrane, ANTcryoTM support membrane has higher particle density, less overlapping of particle dispersion, and shorter data collection time; the particle boundary is clear and the resolution obtained much higher.