suppressor of fused homolog, PRO1280, SuFuH, SuFuXL
SuFu (Suppressor of fused homolog) belongs to the SuFu family. This protein is negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. SuFu has been shown to interact with GLI1, GLI3 and PEX26. Recombina