Recombinant human RCHY1 protein

Product Overview

• Article Name: Recombinant human RCHY1 protein
• Biozol Catalog Number: NBS-PAT-52NNF1-100
• Supplier Catalog Number: PAT-52NNF1-100
• Alternative Catalog Number: NBS-PAT-52NNF1-100
• Manufacturer: Nordic BioSite
• Category: Proteine/Peptide
• Application: EP
• Species Reactivity: Human
• Alternative Names: RING finger and CHY zinc finger domain-containing protein 1, ARNIP, CHIMP, hARNIP, PIRH2, PIRH2E, PIRH2F, PRO1996, RNF199, ZNF363

Product Description

RCHY1 has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript varia

Product Properties

• Concentration: 0.5 mg/ml
• Molecular Weight: 32.5 kDa (284aa)
• Tag: HIS Tag
• NCBI: 25898
• UniProt: Q96PM5
• Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
• Purity: >85%
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAATARE DGASGQERGQ RGCEHYDRGC LLKAPCCDKL YTCRLCHDNN EDHQLDRFKV KEVQCINCEK IQHAQQTCEE CSTLFGEYYC DICHLFDKDK KQYHCENCGI CRIGPKEDFF HCLKCNLCLA MNLQGRHKCI ENVSRQNCPI CLEDIHTSRV VAHVLPCGHL LHRTCYEEML KEGYRCPLCM HSALDMTRYW RQLDDEVAQT P