MDM2 Antibody, IgG1, Clone: [SMP14], Mouse, Monoclonal

Product Overview

• Article Name: MDM2 Antibody, IgG1, Clone: [SMP14], Mouse, Monoclonal
• Biozol Catalog Number: NBT-4193-MSM1-P1ABX
• Supplier Catalog Number: 4193-MSM1-P1ABX
• Alternative Catalog Number: NBT-4193-MSM1-P1ABX-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: ELISA, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthetic peptide (aa 154-167) of human MDM2 protein.
• Alternative Names: ACTFS, Double minute 2 protein, E3 ubiquitin-protein ligase, Hdm2, HDMX, MDM2, MDM2 oncogene E3 ubiquitin protein ligase, MDM2BP, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, p53 Binding Protein Mdm2, p53-binding protein Mdm2

Product Description

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive

Product Properties

• Clonality: Monoclonal
• Clone Designation: [SMP14]
• Molecular Weight: ~90kDa
• Isotype: IgG1
• NCBI: 4193
• UniProt: Q00987
• Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Notes: ELISA (For coating, order antibody without BSA), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45

Images

Western Blot Analysis of human HepG2 cell lysate using MDM2 Mouse Monoclonal Antibody (SMP14).

Formalin-fixed, paraffin-embedded human br