MGMT (Marker of Suppressor of Mutation and Carcinogenesis) Antibody, Clone: [MGMT/8186R], Rabbit, Monoclonal

Product Overview

• Article Name: MGMT (Marker of Suppressor of Mutation and Carcinogenesis) Antibody, Clone: [MGMT/8186R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-4255-RBM8-P1
• Supplier Catalog Number: 4255-RBM8-P1
• Alternative Catalog Number: NBT-4255-RBM8-P1-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant fragment (around aa1-100) of human MGMT (exact sequence is proprietary)
• Alternative Names: 6 O methylguanine DNA methyltransferase, Methylated DNA protein cysteine methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase

Product Description

Cancer chemotherapeutic alkylating agents (e.g. BCNU,) act by inducing formation of lethal cross links at the O6 alkylguanine position in DNA. MGMT transfers alkyl adducts from the O6 position of guanine in DNA (prior to cross link formation) to a c

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MGMT/8186R]
• Molecular Weight: 21.646 kDa
• NCBI: 4255
• UniProt: P16455
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.