Recombinant MLH1 (MutL Homolog 1) / HNPCC Antibody, Clone: [MLH1/6284R], Rabbit, Monoclonal

Product Overview

• Article Name: Recombinant MLH1 (MutL Homolog 1) / HNPCC Antibody, Clone: [MLH1/6284R], Rabbit, Monoclonal
• Biozol Catalog Number: NBT-4292-RBM4-P0
• Supplier Catalog Number: 4292-RBM4-P0
• Alternative Catalog Number: NBT-4292-RBM4-P0-20,NBT-4292-RBM4-P0-100
• Manufacturer: NeoBiotechnologies
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: Recombinant full-length human MLH1 protein
• Alternative Names: COCA2, DNA mismatch repair protein, FCC2, hMLH1, MutL homolog 1 colon cancer nonpolyposis type 2 (HNPCC2)

Product Description

This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MLH1/6284R]
• Molecular Weight: 85kDa
• NCBI: 4292
• UniProt: P40692
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Application Notes

• Application Notes: Western Blot (1-2ug/ml),,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 2

Images

Formalin-fixed, paraffin-embedded human colon carcinoma st