Recombinant DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) Antibody, IgG2b, Clone: [rDG1/447], Mouse, Monoclonal

Product Overview

• Article Name: Recombinant DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) Antibody, IgG2b, Clone: [rDG1/447], Mouse, Monoclonal
• Biozol Catalog Number: NBT-55107-MSM14-P1ABX
• Supplier Catalog Number: 55107-MSM14-P1ABX
• Alternative Catalog Number: NBT-55107-MSM14-P1ABX-100
• Manufacturer: NeoBiotechnologies
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Recombinant full-length human DOG-1 protein
• Alternative Names: Anoctamin 1, Calcium Activated Chloride Channel, Discovered On Gastrointestinal Stromal Tumors Protein 1, TAOS2, ORAOV2, TMEM16A

Product Description

Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST s), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagn

Product Properties

• Clonality: Monoclonal
• Clone Designation: [rDG1/447]
• Molecular Weight: ~114kDa
• Isotype: IgG2b
• NCBI: 55107
• UniProt: Q5XXA6
• Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Application Notes

• Application Notes: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio