Mouse anti P53 (TP53 tumor suppressor protein), Clone: [DO-1], Monoclonal

Product Overview

• Article Name: Mouse anti P53 (TP53 tumor suppressor protein), Clone: [DO-1], Monoclonal
• Biozol Catalog Number: NMB-MUB1501P
• Supplier Catalog Number: MUB1501P
• Alternative Catalog Number: NMB-MUB1501P
• Manufacturer: NordicMubio
• Host: Mouse
• Category: Antikörper
• Application: ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Human

Product Description

P53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Alterations of the p53 tumor suppress

Product Properties

• Clonality: Monoclonal
• Clone Designation: [DO-1]
• Isotype: IgG2a kappa
• UniProt: P04637
• Buffer: Each vial contains 100ul 1mg/ml purified monoclonal antibody in phosphate buffered saline (PBS) containing 0.05% sodium azide. DO-1 recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the w
• Source: DO-1 is a mouse monoclonal IgG2a antibody derived by fusion of mouse myeloma Sp2/0-Ag14 cells with spleen cells from BALB/c mice immunized with recombinant human wild type p53 protein expressed in E. coli.

Application Notes

• Application Notes: The DO-1 antibody is suitable for the detection of p53 by Western blotting and detects a band of 53kDa in tumor tissue and cell extracts. The antibody is suitable for immunocytochemistry on permeabilized cells, and Immunohistochemistry on frozen and form