Recombinant protein corresponding to amino acids 883-1052 of the mouse Bub1b protein.
Conjugation:
Unconjugated
Alternative Names:
Mitotic checkpoint kinase MAD3L
Bub1, a mitotic checkpoint gene first identified in yeast, ensures proper chromosome segregation by delaying anaphase until chromosomes are properly aligned on the mitotic spindle. Mutations in the mitotic spindle assembly checkpoint genes, like yeast Bu
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity:
Ammonium Sulfate Precipitation
Formula:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Application Notes:
Antibody detects Bub1b in mitotic cells seperated from NIH/3T3 cells by IP/Westen blot (1-10 µg/ml) analysis. Detects a 130 kDa band. Optimal concentration should be evaluated by serial dilutions.
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