Bub1, a mitotic checkpoint gene first identified in yeast, ensures proper chromosome segregation by delaying anaphase until chromosomes are properly aligned on the mitotic spindle. Mutations in the mitotic spindle assembly checkpoint genes, like yeast Bu
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Source:
Sheep were immunized with recombinant protein corresponding to amino acids 232-603 of the mouse Bub1b protein.
Purity:
Ammonium Sulfate Precipitation
Formula:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Application Notes:
X1163P antibody detects Bub1b in mitotic NIH/3T3 cells, seperated by immunoprecipitation. Westen blot analysis (1-10 µg/ml) detects a 130 kDa band. Optimal antibody concentration should be evaluated by serial dilutions.
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