Synthetic peptide made to human DNA Topoisomerase 1
DNA Topoisomerase 1 releases the supercoiling and torsional tension of DNA introduced during DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. It introduces a single-strand break via transesterification
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity:
Antigen Immunoaffinity Purification
Formula:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Application Notes:
Antibody can be used for immunohistochemistry at 5-10 µg/ml on paraffin-embedded tissues. Optimal concentration should be evaluated by serial dilutions.
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